Novel Assays for Screening the Effects of Chemical Toxicants on Cell Differentiation (SBIR [R43])

 

This Funding Opportunity Announcement (FOA) solicits Small Business Innovative Research (SBIR) grant applications from small business concerns (SBCs) to develop medium- to high-throughput assays to evaluate the effects of toxicants on pluripotent or induced pluripotent cells with respect to cell differentiation and the resulting differentiated cell populations. The ability to incorporate genetic diversity in these assays would be useful. These assays will provide information on mechanisms of chemically-induced biological activity, help to prioritize chemicals for more extensive toxicological evaluation, support more predictive models of in vivo biological response, and potentially inform on the role of genetic diversity in toxicological effects.

Deleted 03/17/2013 (Archived.) RFA-ES-13-003 Agency: Department of Health and Human Services
Office: National Institutes of Health Grant 02/14/2013 This program does not have cost sharing or matching requirements. NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV
http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-13-003.html FBOWebmaster@OD.NIH.GOV $2,500,000.00 Awards up to $225,000.00