Imaging Diagnostics of Dental Diseases and Conditions (Caries, Periodontal Disease, Cracked Teeth, and Pulp Vitality) (R43/R44)

 

The intent of this SBIR initiative reissue is to accelerate the advanced development and clinical implementation of reliable, reproducible, highly specific and sensitive imaging diagnostic devices for dental caries, periodontal disease, cracked teeth, and pulp vitality. These new devices must demonstrate superior specificity and sensitivity compared with current diagnostic methods, such as the visual/tactile/radiographic examination for detection of caries, while not increasing health risks for patients. Approaches that could be explored include, but are not limited to: optical coherence tomography (OCT) with or without Raman spectroscopy, MRI image analysis, electrical conductivity measurement (ECM), quantitative laser fluorescence (QLF), alternating current impedance spectroscopy, multi-photon imaging, infrared thermography, infrared fluorescence (IR), ultrasound, and terahertz imaging.The development of novel modalities is also encouraged.

Active PA-15-335 Agency: Department of Health and Human Services
Office: National Institutes of Health Grant Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. 09/07/2018 This program does not have cost sharing or matching requirements. NIH OER Webmaster
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