The Autism Research Program (ARP) Idea Development Award supports the development of innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for individuals with autism. This award mechanism is designed to support innovative ideas with the potential to yield impactful data and new avenues of investigation. The FY15 ARP Idea Development Award seeks applications from all areas of basic and preclinical research, and strongly encourages applications that address the critical needs of the autism spectrum disorder (ASD) community in the following areas: Assessment of novel therapeutics using valid preclinical models Environmental risk factors Mechanisms of heterogeneous clinical expression of ASD Mechanisms underlying conditions co-occurring with ASD (e.g., sleep disturbances, gastrointestinal issues, aggression, depression, anxiety) Factors promoting success in key transitions to independence for individuals living with ASD The FY15 ARP supports collaborative research to bring a new perspective to ASD research and/or facilitate progress in the field by combined efforts. Therefore, the FY15 ARP is offering a Multiple PI Option for this award mechanism. The Multiple PI Option is structured so that two investigators, each of whom will be designated as a PI and receive a separate award, will work synergistically on a single project.